Disease Areas

Kidney Disease

Kidney Disease

Kidney disease affects the functions of the kidney, impacting the organ’s ability to filter blood, extra water and wastes out of a person’s system. These conditions can be chronic or acute.1

Our Approach

Through our acquisition of Human Immunology Biosciences (HI-Bio) in July 2024, Biogen officially entered the nephrology space with a portfolio of investigational drugs that target immune-mediated diseases with serious unmet need. Biogen plans to leverage our expertise in immunology, clinical development, and commercialization capabilities to bring these potential new options to patients with these conditions.

Innovative Research

Building on our strong scientific expertise in immunology, we aim to deliver innovative treatments to patients with unmet needs across a range of rare diseases. We know that kidney disease is characterized by a lack of novel treatments with potentially severe consequences – such as end-stage kidney disease or graft failure. For this reason, we are initially focused on addressing three rare kidney diseases with serious unmet needs. 

Facts and Figures

~23k

Approximately twenty-three thousand patients are living with Antibody-Mediated Rejection in the U.S.2

~36k

It is estimated that there are thirty-six thousand patients with Primary Membranous Nephropathy in the U.S.3

 

 

~130k

IgA Nephropathy is the most prevalent glomerular disease estimated to affect ~130k patients in the U.S.4

 

 

 

References
  1. https://www.niddk.nih.gov/health-information/kidney-disease
  2. SRTR; National Institute of Diabetes and Digestive and Kidney Diseases; Department of Health; Hart, Singh. Clin Transplant 2021; Crew. Am J. Transplant. 2016
  3. Based upon Kanigicherla. Nephrol. Dial. Transplant. 2016; McGrogan. Nephrol Dial Transplant. 2011
  4. Based upon Kwon. JHEOR. 2021; Jarrick. Am Soc of Neph. 2019;

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